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But in people with cystic fibrosis, a defective gene causes the secretions to become sticky and thick. Stay informed on the latest rare disease news and developments by signing up for our newsletter. This content does not have an Arabic version. She had Mycobacterium avium pulmonary infection at age 40 and nasal polyps at age She had no hepatosplenomegaly, suprapubic tenderness, or palpable masses. The median survival is 32 years for males and 29 for females.